Comprehensive Pharmacology Services
Our DMPK and Clinical Pharmacology team brings deep expertise in quantitative pharmacology, providing critical insights throughout the drug development lifecycle. We leverage advanced modeling and simulation techniques to inform key decisions from preclinical development through regulatory approval.
Core Capabilities
- Non-compartmental Analysis (NCA)
- Population PK/PD Modeling
- Disease Progression Modeling
- Quantitative Systems Pharmacology (QSP)
Therapeutic Areas
- Oncology
- Cardiovascular & Metabolic Diseases
- Neuroscience
- Rare Diseases
Our Expertise
Non-Compartmental Analysis
Comprehensive NCA services for all phases of clinical development:
- • PK parameter estimation
- • Bioequivalence assessments
- • Food effect studies
- • Drug-drug interaction analysis
- • Special population studies
Population PK/PD Modeling
Advanced population modeling to inform critical development decisions:
- • Dose optimization strategies
- • Covariate analysis
- • Exposure-response relationships
- • Clinical trial simulations
- • Pediatric dose extrapolation
Disease Progression Modeling
Quantitative understanding of disease trajectory and treatment effects:
- • Natural history modeling
- • Biomarker trajectory analysis
- • Treatment effect quantification
- • Long-term outcome predictions
- • Clinical endpoint modeling
Quantitative Systems Pharmacology
Mechanistic modeling to bridge biology and clinical outcomes:
- • Pathway-based modeling
- • Target engagement assessment
- • Combination therapy optimization
- • Translational predictions
- • Biomarker identification
Why Choose Kalvion Sciences for DMPK & Clinical Pharmacology
Scientific Excellence
PhD-level scientists with extensive experience in pharmacometrics and regulatory submissions
Regulatory Expertise
Deep understanding of FDA, EMA, and global regulatory requirements for modeling and simulation
Integrated Approach
Seamless integration with clinical development teams to maximize the impact of pharmacometric analyses
Ready to Optimize Your Drug Development?
Let our experts help you leverage the power of modeling and simulation to make better development decisions.
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